Genetics and Weight

Do genetic factors influence your weight?

Yes! The fit of your jeans is affected at least in part by your genes. Lots of research has shown that genetics not only impacts how much we weigh but also how much diet and exercise may make a difference. Our weight is the product of genetics, lifestyle, and environment all working together.

Healthy habits make a difference.

It’s no secret that eating well and exercising can help control weight. Most people already know that choosing to eat less of certain foods (e.g. fast food, sweets, red meat) and more of others (e.g. veggies and fruit) can make a difference; along with exercising more, sleeping a healthy amount, and managing stress. But did you know that your genes may affect your body’s response to these healthy choices? Some healthy habits may make a bigger difference for your weight than others, based on your own personal genetics.   

Learn more about genetics and your weight

Find out if your genes predispose you to weigh more or less than average with your personalized Genetic Weight Wellness report, available in 23andMe’s Health + Ancestry Service. 23andMe takes into account more than 300 genetic markers to estimate your genetic weight predisposition. And then we go one step further and explore how your genetics may also impact the effect that certain food choices, as well as exercise, sleep, and stress may have on your weight. This info may help you prioritize the healthy habits that could make the biggest difference for you.

Please note:

• The Genetic Weight Wellness report (Powered by 23andMe Research) does not diagnose any health conditions or provide medical advice. Always consult with a healthcare professional before making any major lifestyle changes.
• The report was developed by 23andMe scientists using data and insights gathered from thousands of customers who consent to participate in research. It provides a weight predisposition score and a healthy habits analysis based on your genetics and other factors.
• The report does not account for every possible genetic variant that could affect your weight nor every possible lifestyle factor that has an impact on health and weight.

References

Nettleton J et al. (2015). “Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry.” Hum Mol Genet. 24(16):4728-38. 

Reddon H et al. (2016). “Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study.” Sci Rep. Jan 4;6:18672. 

U.S. Department of Health and Human Services and U.S. Department of Agriculture. “2015-2020 Dietary Guidelines for Americans.” 8th Edition. December 2015. 

U.S. Department of Health and Human Services. “2008 Physical Activity Guidelines for Americans.” 2008.