Is FH genetic? Yes. FH is one of the most common genetic conditions. FH is linked to variants (differences) in multiple genes. Two of these genes are called APOB and LDLR. There are over 1,000 genetic variants known to be associated with FH. FH is serious, and many don’t know they have it. Most people… Continue reading Familial Hypercholesterolemia & Genetics
Category: Health Predispositions
Learn how genetics can impact the chances of developing certain health conditions.
These topic pages include information on conditions highlighted in 23andMe Genetic Health Risk reports (which meet FDA requirements) and reports powered by 23andMe research.
Celiac Disease
Is celiac disease genetic? Genetics play a role in celiac disease. Variants (differences) in two genes can influence the risk of developing celiac disease. These genes are called HLA-DQA1 and HLA-DQB1, and they help the immune system respond to invaders such as viruses and bacteria. Other factors related to celiac disease In people with a… Continue reading Celiac Disease
Alpha-1 Antitrypsin Deficiency
Is AAT deficiency genetic? Yes. AAT deficiency is caused by genetic variants (differences) in the SERPINA1 gene. The SERPINA1 gene contains instructions for making a protein called alpha-1 antitrypsin (AAT). This protein is made in the liver and is transported to the lungs where it helps protect lungs from damage. Certain genetic variants in the… Continue reading Alpha-1 Antitrypsin Deficiency
